Search on: BRUNO-LIKE 2 PROTEIN 
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Descriptor English:   CELF1 Protein 
Descriptor Spanish:   Proteínas CELF1 
Descriptor Portuguese:   Proteínas CELF1 
Synonyms English:   BRUNOL2 Protein
Bruno-Like 2 Protein
CUG Triplet Repeat, RNA-Binding Protein 1
CUGBP, Elav-Like Family Member 1 Protein
CUGBP1 Protein
2 Protein, Bruno-Like
Bruno Like 2 Protein
CUG Triplet Repeat, RNA Binding Protein 1
CUGBP, Elav Like Family Member 1 Protein
Protein, BRUNOL2
Protein, Bruno-Like 2
Protein, CELF1
Protein, CUGBP1  
Tree Number:   D12.776.157.725.813.250.500
D12.776.664.962.813.250.500
Definition English:   A member of the CELF PROTEINS family which binds GU rich elements (GREs) and CUG-triplet repeats in the 3'UTR of mammalian mRNA transcripts that undergo rapid turnover. It also binds AU-rich elements (AREs or EDEN-like) in the 3'UTR of JUN and FOS mRNAs. Mutations in the human CELF1 gene are associated with MYOTONIC DYSTROPHY type 1. 
History Note English:   2016 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55989 
Unique Identifier:   D000067879 

Occurrence in VHL: 		 

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